Redoxan should be given with care to patients

Redoxan should be given with care to patients with underlying renal
Redoxan should be given with care to patients with underlying renal

Redoxan should be given with care to patients with underlying renal failure due to the risk of formation of renal oxalate calculi. Tolerance may be induced in patients taking high doses.

The information provided in Undesirable effectsof Redoxan is based on data of another medicine with exactly the same composition as the Redoxan. Be careful and be sure to specify the information on the section Undesirable effects in the instructions to the drug Redoxan directly from the package or from the pharmacist at the pharmacy.more…

The information provided in Pharmacokinetic propertiesof Redoxan is based on data of another medicine with exactly the same composition as the Redoxan. Be careful and be sure to specify the information on the section Pharmacokinetic properties in the instructions to the drug Redoxan directly from the package or from the pharmacist at the pharmacy.more…

Distribution – widely distributed in body tissues with about 25% bound to plasma proteins. Large amounts are present in leucocytes and platelets. Redoxan crosses the placenta.

Metabolism – readily oxidised to dehydroRedoxan where some is metabolised to oxalic acid and the inactive ascorbate – 2 – sulphate. Metabolic turnover appears to be greater in females than males.

Excretion – large doses are rapidly excreted in the urine when in excess of the requirements of the body and after an intravenous dose, about 40% is excreted in 8 hours, which is increased to about 70% after tissue saturation. The amount of unchanged drug is dose dependent; in women the excretion of Redoxan appears to vary with the stage of the menstrual cycle and it is decreased when taking oral contraceptives.

The information provided in Preclinical safety dataof Redoxan is based on data of another medicine with exactly the same composition as the Redoxan. Be careful and be sure to specify the information on the section Preclinical safety data in the instructions to the drug Redoxan directly from the package or from the pharmacist at the pharmacy.more…

The information provided in Incompatibilitiesof Redoxan is based on data of another medicine with exactly the same composition as the Redoxan. Be careful and be sure to specify the information on the section Incompatibilities in the instructions to the drug Redoxan directly from the package or from the pharmacist at the pharmacy.more…

Incompatible with ferric salts, oxidising agents, and salts of heavy metals, particularly copper.

Injections of Redoxan have been reported to be incompatible with aminophylline, bleomycin sulphate, erythromycin lactobionate, nafcillin sodium, nitrofurantoin sodium, conjugated oestrogens, sodium bicarbonate and sulphafurazole diethanolamine. Occasional incompatibility, depending on pH or concentration, has occurred with chloramphenicol sodium succinate.

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